Sexual orientation of 46, XX patients with congenital adrenal hyperplasia: a descriptive review. Issue 6 (December 2018)

• Record Type: Journal Article
• Authors: Gondim, R.; Teles, F.; Barroso, U.
• Is Part Of: Journal of pediatric urology. Volume 14:Issue 6(2018)
• Page Start: 486
• Page End: 493
• Publication Date: 2018-12
• Subjects: Congenital adrenal hyperplasia -- Sexual orientation -- Prader; Pediatric urology -- Periodicals; Urologic Diseases -- Periodicals; Urogenital Diseases -- Periodicals; Urologic Surgical Procedures -- Periodicals; Child; Infant; Urologie pédiatrique -- Périodiques; Appareil urinaire -- Maladies -- Périodiques; Pédiatrie; Urologie; Pediatric urology; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); Electronic journals; Periodicals; Electronic journals; 618.926
• DOI: 10.1016/j.jpurol.2018.08.004
• Languages: English
• ISSNs: 1477-5131

Abstract

Summary: Background: Congenital adrenal hyperplasia (CAH) consists of a group of diseases characterized by an enzyme deficiency, particularly 21-hydroxylase deficiency. The condition may present in the simple virilizing form or in the salt-wasting form, with varying degrees of genital ambiguity. The non-heterosexual orientation is used in gender studies fields and includes bisexual, homosexual, Lesbians, gays, bissexuals, transgender, intersex, and others. Objective: The objective of this study was to evaluate the frequency of non-heterosexual orientation in patients with CAH, in an attempt to identify biological factors possibly associated with this occurrence. Methods: This was a descriptive review of observational studies on the sexual orientation of patients with CAH published between 1985 and 2016, as listed in PubMed. Results: Various studies have been performed to establish the relationship between CAH and non-heterosexual orientation. Non-heterosexual orientation is more prevalent in patients with more advanced Prader stages and those with the null and I2-splice genotype. Conclusion: The prevalence of homosexuality and bisexuality is greater in patients with CAH in relation to the general population.