Treatment of primary hepatic neuroendocrine tumors with associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): A case report and literature review. Issue 37 (September 2018)

• Record Type: Journal Article
• Authors: Qu, Chao; Qu, Lin-lin; Zhu, Cheng-zhan; Wang, Zu-sen; Cao, Jingyu
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 97:Issue 37(2018)
• Publication Date: 2018-09
• Subjects: associating liver partition and portal vein ligation for staged hepatectomy -- primary hepatic neuroendocrine tumors -- surgery treatment; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000012408
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Primary hepatic neuroendocrine tumors (PHNETs) are extremely rare and are difficult to diagnose preoperatively.We report a case of PHNET diagnosed preoperatively and successfully resected using associating liver partition and portal vein ligation for staged hepatectomy (ALPPS). Patient concerns: A 72-year-old woman was admitted to our hospital for a hepatic mass, which was incidentally identified during a routine health checkup. The patient has no other obvious symptoms of discomfort. Diagnoses: Physical examination revealed a palpable mass in the right upper quadrant of her abdomen. Dynamic contrast-enhanced abdominal computed tomography (CT) showed a low-density mass measuring 13 × 7 × 6 cm in both, the right and left hepatic lobes. 18 F-fluorodesoxyglucose positron emission tomography ( 18 F-FDG PET) and fused PET/CT showed increased uptake by the mass, which was indicative of a hepatic tumor. Interventions: We use a novel ALPPS surgical procedure to safely and radically remove primary neuroendocrine tumors. Outcomes: No postoperative bleeding and bile leakage were reported, and the patient recovered uneventfully.The patient was followed-up for a year without recurrence. Lessons: PHNETs are rare tumors, and confirming the diagnosis using the best possible preoperative examination is important. An optimal treatment plan is selected based on the patient's condition to ensure a favorable prognosis. Tumors too large to undergo surgical removal can be resected using the ALPPS procedure, as described in this case report.