A Rare Case of Spontaneous Remission of Terminal Deoxynucleotidyl Transferase Negative B-acute Lymphoblastic Leukemia. Issue 3 (April 2018)

• Record Type: Journal Article
• Authors: Iqbal, Asneha; Weinstein, Joanna; Angelova, Victoria; Dighe, Dipti; Giordano, Lisa
• Is Part Of: Journal of pediatric hematology/oncology. Volume 40:Issue 3(2018)
• Publication Date: 2018-04
• Subjects: spontaneous -- remission -- lymphoblastic -- leukemia -- terminal deoxynucleotidyl transferase; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000000906
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Spontaneous remission of untreated pediatric leukemia is an extremely rare occurrence. The underlying mechanism may be because of an immune-mediated process or increased cortisol production during stress or infection. We describe a rare case of terminal deoxynucleotidyl transferase negative B-acute lymphoblastic leukemia with concurrent infection that went into remission without treatment with chemotherapy or corticosteroids. Though B-acute lymphoblastic leukemia can rarely go into spontaneous remission, these patients require close follow-up as most patients will eventually develop recurrence.