Hepatic Legionella pneumophila Infection in an Infant With Severe Combined Immunodeficiency. Issue 4 (April 2018)

• Record Type: Journal Article
• Authors: Lapidot, Rotem; Alawdah, Laila; Köhler, J. R.; Paulson, Vera; Levy, Ofer
• Is Part Of: Pediatric infectious disease journal. Volume 37:Issue 4(2018)
• Publication Date: 2018-04
• Subjects: Legionella pneumophila -- liver lesions -- severe combined immunodeficiency -- reticular dysgenesis; Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000001789
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : Rare cases of extrapulmonary involvement in Legionella spp. infections have been described, mostly in immunocompromised adults. We report a case of a 2-month old male with reticular dysgenesis variant of severe combined immune deficiency with multiple liver lesions. Core-needle biopsies of one liver lesion demonstrated Gram-negative bacilli and a broad-spectrum polymerase chain reaction assay detected Legionella pneumophila .