Alkane Carbon‐Hydrogen Bond Functionalization as a Tool Toward a Steric Parameter for Hydrotris(pyrazolyl)borate (Tpx) Ligands. Issue 10 (18th October 2017)

• Record Type: Journal Article
• Authors: Caballero, Ana; Pérez, Pedro J.
• Is Part Of: Israel journal of chemistry. Volume 57:Issue 10/11(2017)
• Page Start: 1047
• Page End: 1052
• Publication Date: 2017-10-18
• Subjects: steric parameter -- hydrotris(pyrazolyl)borate ligands -- C−H functionalization -- carbene transfer -- nitrene transfer; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/ijch.201700110
• Languages: English
• ISSNs: 0021-2148

Abstract

Abstract: The effect of a series of hydrotris(pyrazolyl)borate ligands (Tp x ) in the regioselectivity of the catalytic functionalization of the secondary carbon‐hydrogen bonds of hexane with ethyl diazoacetate and Tp x CuL as the catalysts has led to the definition of the relative steric parameter SPR . The validity of the parameter has been assessed upon its correlation with the regioselectivity observed in several transformations (olefin cyclopropanation, C−H functionalization, C−H amidation), in all cases a good degree of fitting being observed. Abstract :