Cytotoxicity and Structural Analyses of 2, 2′‐Bipyridine‐, 4, 4′‐Dimethyl‐2, 2′‐bipyr­idine‐ and 2‐(2′‐Pyridyl)quinoxalineplatinum(II) Complexes (Eur. J. Inorg. Chem. 25/2015). Issue 25 (September 2015)

• Record Type: Journal Article
• Authors: Pages, Benjamin J.; Zhang, Yingjie; Li, Feng; Sakoff, Jennette; Gilbert, Jayne; Aldrich‐Wright, Janice R.
• Is Part Of: European journal of inorganic chemistry. Issue 25(2015)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2015-09
• Subjects: Medicinal chemistry -- Antitumor agents -- Cytotoxicity -- Aggregation -- Platinum; Chemistry, Inorganic -- Periodicals; Organometallic chemistry -- Periodicals; Bioinorganic chemistry -- Periodicals; Solid state chemistry -- Periodicals; 546
• DOI: 10.1002/ejic.201590098
• Languages: English
• ISSNs: 1434-1948

Abstract

Abstract : The cover picture shows X‐ray crystal structures contrasting the differences in stacking and coordination geometry of platinum(II) complexes of 4, 4'‐dimethyl‐2, 2'‐bipyridine and 2‐(2'‐pyridyl)quinoxaline. The CD spectra emphasise the effect that such structural differences can have upon the electronic properties of the compounds. Fluorescently stained HT29 human colon carcinoma cells make up the background, demonstrating the application of the complexes as anticancer agents. Finally, the Southern Cross refers to the country of origin of this work, while the yellow stars represent our acknowledgement to this journal and the European Union. Details are discussed in the article by J. R. Aldrich‐Wright et al. onp. 4167 ff . For more on the story behind the cover research, see theCover Profile .