An Air‐Stable Nickel(0) Phosphite Precatalyst for Primary Alkylamine C–N Cross‐Coupling Reactions. Issue 27 (September 2015) - Kampmann, Sven S.
Abstract: In this report we describe the design and preparation of a new air‐stable nickel phosphite based catalyst for unique C–N bond forming processes. Specifically, (BINAP)Ni[P(OPh)3 ]2, is presented as an effective catalyst for a range of amination reactions between aryl halides and primary alkylamines. The results are supported by relevant kinetic studies, DFT calculations and a catalytic cycle indicating possible reaction intermediates. Abstract : The amination reaction between a series of aryl halides and primary alkylamines is described using a new air‐stable nickel phosphite based catalyst (BINAP)Ni[P(OPh)3 ]2 .