B(C6F5)3-catalyzed Markovnikov addition of indoles to aryl alkynes: an approach toward bis(indolyl)alkanes. Issue 47 (28th November 2018)

• Record Type: Journal Article
• Authors: Ling, Fei; Xiao, Lian; Fang, Lu; Feng, Cong; Xie, Zhen; Lv, Yaping; Zhong, Weihui
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 47(2018)
• Page Start: 9274
• Page End: 9278
• Publication Date: 2018-11-28
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob02805b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The B(C6 F5 )3 -catalyzed Markovnikov addition of indoles to aryl alkynes was achieved, leading to a wide spectrum of versatile bis(indolyl)alkanes in moderate to good yields with high regioselectivities. Abstract : The first example of the metal- and solvent-free B(C6 F5 )3 -catalyzed Markovnikov addition of indoles to aryl alkynes was disclosed. Both N –H and N -protected indoles were tolerated, leading to a wide spectrum of versatile bis(indolyl)alkanes in moderate to good yields with high regioselectivities.