Unilateral Posterior Interstitial Keratitis as a Clinical Presentation of Herpes Simplex Virus Disease. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Farooq, Asim V.; Paley, Grace L.; Lubniewski, Anthony J.; Gonzales, John A.; Margolis, Todd P.
• Is Part Of: Cornea. Volume 37:Issue 3(2018)
• Publication Date: 2018-03
• Subjects: herpes simplex virus -- stromal keratitis -- interstitial keratitis -- posterior stromal keratitis -- neurotrophic keratitis; Cornea -- Periodicals; Cornea -- Periodicals; Cornée -- Périodiques; 617.719
• DOI: 10.1097/ICO.0000000000001499
• Languages: English
• ISSNs: 0277-3740

Abstract

Abstract : Purpose: To describe a case series of patients with unilateral, posterior interstitial keratitis presumed to be caused by herpes simplex virus. Methods: Retrospective case series. Results: Five patients were found to have unilateral, posterior interstitial keratitis. Three of the involved eyes had decreased corneal sensation, and 2 eyes had corneal stromal neovascularization. All patients were treated with topical steroids and an oral antiviral, and among those with long-term follow-up, clinical improvement required treatment over an extended duration. A review of the literature revealed 1 reported case with a similar clinical appearance, although that case was attributed to Lyme disease. Conclusions: The clinical presentation of unilateral, posterior interstitial keratitis may be a rare manifestation of herpes simplex virus keratitis.