Changing patterns in treatment of angle closure glaucoma. Issue 2 (March 2018)

• Record Type: Journal Article
• Authors: Napier, Maria L.; Azuara-Blanco, Augusto
• Is Part Of: Current opinion in ophthalmology. Volume 29:Issue 2(2018)
• Publication Date: 2018-03
• Subjects: angle closure glaucoma -- anterior chamber angle -- argon laser peripheral iridoplasty -- intraocular pressure -- laser peripheral iridotomy -- lens extraction -- lens extraction; Ophthalmology -- Periodicals; Eye Diseases -- Indexes; Eye Diseases -- Periodicals; Review Literature -- Indexes; Review Literature -- Periodicals; Vision Disorders -- Indexes; Vision Disorders -- Periodicals; 617.7
• DOI: 10.1097/ICU.0000000000000453
• Languages: English
• ISSNs: 1040-8738

Abstract

Abstract : Purpose of review: Angle closure glaucoma is a leading cause of blindness globally and trends of how best to treat this disease are evolving. The advent of anterior segment imaging aids our understanding of pathogenesis and allows more robust and objective measurement of treatment modalities. We will also review recent literature regarding the role of laser and surgical interventions for the treatment of primary angle closure disease. Recent findings: Recent studies evaluating the efficacy of laser peripheral iridotomy (LPI) in primary angle closure suspects (PACs) show that while it is a safe intervention and initially anterior chamber angle widens following the laser treatment, the effect is lost with time. Only a small minority of PACs patients develop primary angle closure (PAC) or primary angle closure glaucoma (PACG). Trials evaluating argon laser peripheral iridoplasty (ALPI) have failed to show a substantial clinical benefit. In patients with early or moderate PACG and those with PAC with IOP over 30 mmHg, clear lens extraction is associated with better clinical and quality of life outcomes than LPI. Summary: Recent evidence supports initial clear lens extraction in the context of PACG or primary angle closure with IOP more than 30 mmHg.