Multimodal Approach for Treating Horizontal Neck Wrinkles Using Intensity Focused Ultrasound, Cohesive Polydensified Matrix Hyaluronic Acid, and IncobotulinumtoxinA. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Jeon, Heedae; Kim, Taeyoon; Kim, Heesu; Cho, Sung Bin
• Is Part Of: Dermatologic surgery. Volume 44:Issue 3(2018)
• Publication Date: 2018-03
• Subjects: Skin -- Surgery -- Periodicals; Skin -- Diseases -- Surgery -- Periodicals; 617.477
• DOI: 10.1097/DSS.0000000000001312
• Languages: English
• ISSNs: 1076-0512

Abstract

Abstract : BACKGROUND: For the restoration of horizontal neck wrinkles, multimodal approaches using neuromodulators, intensity focused ultrasound (IFU), and fine line fillers are recommended. OBJECTIVE: To evaluate the efficacy and safety of a 1-day, multimodal approach for horizontal neck wrinkles. METHODS: Twelve female patients with horizontal neck wrinkles were treated with a combined treatment of IFU, cohesive polydensified matrix hyaluronic acid (CPMHA), and incobotulinumtoxinA. Therapeutic outcomes were assessed on Day 0 and 1, 2, 3, and 6 months thereafter. RESULTS: Horizontal neck wrinkles decreased significantly in length from a median at baseline of 269.75 mm (interquatile range [IQR], 235.35–302.94 mm) to 91.5 mm (IQR, 51.4–108.61 mm) at 1 month, 92.3 mm (IQR, 69.66–132.07 mm) at 2 months, 101.88 mm (IQR, 86–146.77 mm) at 3 months, and 109.48 mm (IQR, 85.06–148.17 mm) at 6 months after the combined treatment. The median global aesthetic improvement scale scores were 3.5 (IQR, 2–4) at 1 month, 3 (IQR, 3–3.5) at 2 months, 3 (IQR, 2–4) at 3 months, and 3 (IQR, 3–3) at 6 months. Post-treatment petechiae resolved completely within 7 days, and CPMHA-induced lumps disappeared within 1 month. CONCLUSION: The present data demonstrated that the multimodal, combined treatment used in the present study provides satisfactory and long-lasting therapeutic outcomes by targeting different pathogenetic factors of horizontal neck wrinkles.