Adherence to a Gluten-free Diet: Assessment by Dietician Interview and Serology. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Mehta, Pooja; Pan, Zhaoxing; Riley, Marisa D.; Liu, Edwin
• Is Part Of: Journal of pediatric gastroenterology and nutrition. Volume 66:Issue 3(2018)
• Publication Date: 2018-03
• Subjects: celiac disease -- compliance -- gluten-free diet -- tissue transglutaminase; Children -- Nutrition -- Periodicals; Pediatric gastroenterology -- Periodicals; Infants -- Nutrition -- Periodicals; Nutrition disorders in children -- Periodicals; Child Nutrition -- Periodicals; Digestive System -- growth & development -- Periodicals; Gastrointestinal Diseases -- Periodicals; Infant Nutrition -- Periodicals; Nutrition Disorders -- Periodicals; Child; 618.923
• DOI: 10.1097/MPG.0000000000001705
• Languages: English
• ISSNs: 0277-2116

Abstract

Abstract : ABSTRACT: We aimed to determine whether tissue transglutaminase (tTG) autoantibody positivity was associated with dietitian-assessed adherence to a gluten-free diet in pediatric patients with celiac disease and identify areas where adherence falters. We reviewed the records of children with celiac disease who had a standardized evaluation of adherence by a registered dietitian. A negative tTG value was not associated with good adherence ( P = NS). Adherent and nonadherent children differed with respect to purposeful and accidental gluten exposure ( P < 0.0001), knowledge ( P = 0.003), cross-contact ( P = 0.003), potential exposure via medications and cosmetics ( P = 0.004), and potential exposure while at restaurants ( P < 0.0001), but not with respect to potential exposure at school ( P = NS). Based on our findings, we suggest that negative tTG levels are not necessarily indicative of good adherence to a gluten-free diet in pediatric patients with celiac disease. A separate assessment of adherence is needed focusing on knowledge, behavior while dining out, and intent to adhere. Abstract : Supplemental Digital Content is available in the text