Easy degradable polymeric gel with extremely base-labile cross-linking. (9th March 2015)

• Record Type: Journal Article
• Authors: Chang, Ruixue; Li, Na; Qin, Jianglei; Wang, Haijun
• Is Part Of: Polymer. Volume 60(2015)
• Page Start: 62
• Page End: 68
• Publication Date: 2015-03-09
• Subjects: Degradable cross-linking -- Phenolic ester -- Chemical gel; Polymers -- Periodicals; Polymerization -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; 547.7
• DOI: 10.1016/j.polymer.2015.01.037
• Languages: English
• ISSNs: 0032-3861

Abstract

Abstract: A variety of cross-linkable block copolymers were studied to prepare cross-linked structure and nanoobjects which are stable in solvents; at the same time, some degradable core cross-linked star polymers and gels which can be degraded under catalysis were also reported. In this study, degradable chemical cross-linked poly( tert -butyl acrylate) gels were prepared with phenolic ester linkage, which can be cleaved effectively under extremely mild condition of NaHCO3 . Post cross-linked gel was prepared via microphase separation of cross-linkable phenolic ester containing poly(glycidyl methacrylate)-(phenolic ester)poly( tert -butyl acrylate)-poly(glycidyl methacrylate) (PGMA-(PE)P t BA-PGMA) triblock copolymer, which was synthesized by atom transfer radical polymerization (ATRP). After microphase separation, the low volume ratio of PGMA formed nanospheres dispersed in the P t BA matrix and cross-linked by amine; chemical cross-linked gel was then obtained after swelling. In situ polymeric gel with higher phenolic ester bond density was prepared by copolymerization of t BA and phenolic ester containing difunctional monomer hydroquinone diacrylate (HDA) as cross-linker. These chemical cross-linked gels can be degraded into dispersed nanospheres and linear P t BA separately in NaHCO3 /methanol. Moreover, the cross-linked gels can be hydrolyzed into PAA hydrogels by CF3 COOH which can be degraded effectively by NaHCO3 /H2 O solution. Graphical abstract: Highlights: We prepared new kinds of degradable cross-linked polymeric gels. The gels were cross-linked with phenolic ester linkage. The polymeric gels with high ratio of P t BA can be degraded by NaHCO3 in methanol. These gels can be degraded by NaHCO3 /H2 O after P t BA was hydrolyzed into PAA.