Rhodium(II)-catalyzed transannulation of 1-sulfonyl-1, 2, 3-triazoles with 2H-azirines: a new method to dihydropyrazines. Issue 3 (14th January 2015)

• Record Type: Journal Article
• Authors: Ding, Haixin; Hong, Sanguo; Zhang, Ning
• Is Part Of: Tetrahedron letters. Volume 56:Issue 3(2015)
• Page Start: 507
• Page End: 510
• Publication Date: 2015-01-14
• Subjects: Transannulation -- 1-Sulfonyl-1, 2, 3-trizaole -- Dihydropyrazine -- 2H-Azirine -- Rhodium; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2014.12.032
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: An efficient rhodium(II)-catalyzed transannulation method of 1-sulfonyl-1, 2, 3-triazoles with 2 H -azirines has been utilized for the synthesis of phenyl-substituted dihydropyrazines. The dihydropyrazine products can be further converted to pyrazines under basic conditions in excellent yield.