Unsuspected Metastases to Muscles in Osteosarcoma Detected on 18F-Sodium Fluoride PET-CT. (September 2018)

• Record Type: Journal Article
• Authors: Usmani, Sharjeel; Marafi, Fahad; Rasheed, Rashid; Bakiratharajan, David; Al Maraghy, Muneera; Al Kandari, Fareeda
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 9(2018)
• Publication Date: 2018-09
• Subjects: 18F-NaF PET-CT -- extraosseous uptake -- metastatic osteosarcoma; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002191
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Metastasis of osteosarcoma to the muscles is extremely rare. 18 F-sodium fluoride (NaF) is a bone-seeking agent that can also localize extraosseous calcifying lesions. We report the case of a 33-year-old woman with osteosarcoma of the right fibula treated with surgery and chemotherapy 2 years back who was referred for 18 F-NaF PET-CT to evaluate possible metastatic lesions. 18 F-NaF PET-CT unexpectedly detected 2 foci of soft tissue increased tracer uptake in the right lateral abdominal and left paraspinal muscles, which corresponded to the focal calcification in the muscles. The pathological examination revealed metastatic osteosarcoma to the muscles.