Influence of Sociodemographic Factors on Disease Characteristics and Vision-related Quality of Life in Primary Open-angle Glaucoma Patients: The Italian Primary Open Angle Glaucoma Study (IPOAGS). Issue 9 (September 2018)

• Record Type: Journal Article
• Authors: Riva, Ivano; Legramandi, Lorenzo; Katsanos, Andreas; Oddone, Francesco; Rulli, Eliana; Roberti, Gloria; Quaranta, Luciano
• Is Part Of: Journal of glaucoma. Volume 27:Issue 9(2018)
• Publication Date: 2018-09
• Subjects: glaucoma -- quality of life -- sociodemographic factors; Glaucoma -- Periodicals; 617.741005
• DOI: 10.1097/IJG.0000000000000989
• Languages: English
• ISSNs: 1057-0829

Abstract

Abstract : Purpose: The purpose of this article was to evaluate the potential association between sociodemographic factors with clinical characteristics, vision-related quality of life (QoL), and glaucoma-related symptoms scores in a large cohort of primary open-angle glaucoma patients. Materials and Methods: Multicenter, cross-sectional study involving academic and nonacademic centers. Previously diagnosed primary open-angle glaucoma patients aged >18 years were enrolled. At baseline, information on demographic characteristics, social, medical and ocular history, clinical presentation and treatments was collected. Vision-related QoL was evaluated by means of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), while glaucoma-related symptoms were evaluated using the Glaucoma Symptom Scale (GSS) questionnaire. The associations between sociodemographic factors with clinical characteristics (mean deviation, pattern standard deviation, best-corrected visual acuity), NEI-VFQ-25, and GSS scores were evaluated by means of univariate and multivariate general linear models. Results: A total of 3227 patients were enrolled. Older age and male sex were significantly associated with lower mean deviation ( P <0.01) and higher pattern standard deviation ( P <0.01), whereas older age was associated with lower best-corrected visual acuity ( P <0.01). The composite GSS score was related to age ( P =0.02), sex ( P <0.01), employment ( P =0.01), and profession ( P =0.04), while the total NEI-VFQ-25 score was associated with sex ( P <0.01), marital status ( P =0.02), and employment ( P =0.02). Conclusions: Age and sex were significantly associated with almost all indicators of glaucoma severity at baseline. Other variables, such as employment, profession, and marital status were significantly associated with vision-related QoL scores. Abstract : Supplemental Digital Content is available in the text.