Propagation Loss‐Immune Biocompatible Nanodiamond Refractive Index Sensors. Issue 5 (4th January 2018)

• Record Type: Journal Article
• Authors: Shugayev, Roman; Bermel, Peter
• Is Part Of: Advanced optical materials. Volume 6:Issue 5(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-01-04
• Subjects: deep tissue imaging -- diamond color centers -- fluorescence lifetime imaging -- nanodisks -- nontargeted fluorescent probes; Optical materials -- Periodicals; Photonics -- Periodicals; 620.11295
• DOI: 10.1002/adom.201700487
• Languages: English
• ISSNs: 2195-1071

Abstract

Abstract: Propagation loss is a key impeding parameter affecting accuracy, range, and applicability of fluorescent microscopy techniques. In this work, a new nanophotonic platform for propagation loss mitigated fluorescent imaging using lifetime ratiometric measurement is proposed. By applying this methodology to local parameter sensing, a method for high sensitivity local refractive index measurement via lifetime/energy monitoring of fluorescent crystal color centers is numerically demonstrated. As the base of this platform, biocompatible diamond nanodisk structures are investigated that enable sensitive, propagation loss‐immune monitoring of refractive index changes both in vitro and in vivo. Abstract : Propagation loss is a key impeding parameter affecting accuracy, range, and applicability of fluorescent microscopy techniques. In this work, a new nanophotonic platform is proposed for propagation loss mitigated fluorescent imaging using lifetime ratiometric measurement. As the base of this platform, diamond color center nanodisk structures that enable sensitive, propagation loss‐immune monitoring of refractive index changes both in vitro and in vivo are investigated.