Prenatal thrombosis of renal veins and the inferior vena cava in a newborn with double heterozygosity for the factor V Leiden and prothrombin gene G20210A mutations: a case report. Issue 2 (March 2018)

• Record Type: Journal Article
• Authors: Bulut, Ozgul; Ince, Zeynep; Uzunhan, Ozan; Coban, Asuman
• Is Part Of: Blood coagulation and fibrinolysis. Volume 29:Issue 2(2018)
• Publication Date: 2018-03
• Subjects: factor V Leiden -- mutations -- newborn -- prenatal thrombosis -- prothrombin gene; Blood -- Coagulation -- Periodicals; Fibrinolysis -- Periodicals; Hemostasis -- Periodicals; Thrombosis -- Periodicals; Blood Coagulation -- Periodicals; Fibrinolysis -- Periodicals; Hemostasis -- Periodicals; Thrombosis -- Periodicals; 612.115
• DOI: 10.1097/MBC.0000000000000686
• Languages: English
• ISSNs: 0957-5235

Abstract

Abstract : N/A: Renal vein thrombosis in a neonate is a rare but well recognized condition with low mortality but high morbidity. The cause has not been explained clearly yet but is probably a multifactorial process that includes inherited prothrombotic abnormalities. Antenatal onset of renal vein thrombosis is important due to the increased risk for permanent organ damage. We report a case of prenatal thrombosis of the renal veins and the inferior vena cava in a newborn with double heterozygosity for factor V Leiden and prothrombin gene mutations who had persistently impaired renal function requiring chronic peritoneal dialysis.