Theranostic Gold Nanomicelles made from Biocompatible Comb‐like Polymers for Thermochemotherapy and Multifunctional Imaging with Rapid Clearance. (6th May 2015)

• Record Type: Journal Article
• Authors: Deng, Heng; Dai, Fengying; Ma, Guanghui; Zhang, Xin
• Is Part Of: Advanced materials. Volume 27:Number 24(2015)
• Page Start: 3645
• Page End: 3653
• Publication Date: 2015-05-06
• Subjects: clearance -- comb‐like polymers -- gold nanoparticles -- self‐assembly -- theranostics; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201501420
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : A new generation of photothermal theranostic agent s based on assembling 6 nm gold nanoparticles (AuNPs) is developed by using a novel comb‐like amphipathic polymer as the template. The small AuNPs are assembled into DOX@gold nanomicelles, which show strong absorbance in the near‐infrared region, for multimodal bioimaging and highly effective in vivo chemotherapy and photothermal therapy.