Fertility management for malignant ovarian germ cell tumors patients. (December 2017)

• Record Type: Journal Article
• Authors: Di Tucci, Chiara; Casorelli, Assunta; Morrocchi, Elisa; Palaia, Innocenza; Muzii, Ludovico; Panici, Pierluigi Benedetti
• Is Part Of: Critical reviews in oncology/hematology. Volume 120(2017)
• Page Start: 34
• Page End: 42
• Publication Date: 2017-12
• Subjects: Ovarian cancer -- Ovarian germ cell tumor -- Germ cell cancer -- Fertility -- Management -- Treatment; Oncology -- Periodicals; Hematology -- Periodicals; 616.994
• DOI: 10.1016/j.critrevonc.2017.10.005
• Languages: English
• ISSNs: 1040-8428

Abstract

Highlights: Fertility management of patients with malignant ovarian germ cell cancer. Patients with malignant ovarian germ cell cancer underwent surgical and/or medical treatment. Tailoring fertility management are need in patients underwent treatment for malignat ovarian germ cell tumor. Abstract: Malignant Germ Cell Tumors have primarily affecting adolescents and young adults. In advanced disease, greater than 70% of patients can be cured with standard chemotherapy regimens and fertility-sparing surgery appears to be safe with excellent survival after long-term follow-up. Due to their rarity, follow up and fertility management is largely based on trials of epithelial ovarian cancer or on few small studies. We report a review of the literature studies about the assessment, the monitoring and the treatment of fertility for Malignant Germ Cell Tumors as pratical guidelines for management of fertility in these patients.