Dimethyl fumarate treatment alters NK cell function in multiple sclerosis. Issue 2 (15th December 2017) - Smith, Matthew D.
Abstract : Dimethyl fumarate (DMF) treatment in multiple sclerosis (MS) increased the proportion of immunoregulatory CD56 bright NK cells and this change was proportional to reductions in CD8 + memory T cells. DMF and monomethyl fumarate (MMF) treatment in vitro had directs effects on NK cells and promoted degranulation and cytotoxicity.