History of mood or anxiety disorders and risk of gestational diabetes mellitus in a population‐based cohort. Issue 1 (10th December 2017)

• Record Type: Journal Article
• Authors: Beka, Q.; Bowker, S. L.; Savu, A.; Kingston, D.; Johnson, J. A.; Kaul, P.
• Is Part Of: Diabetic medicine. Volume 35:Issue 1(2018)
• Page Start: 147
• Page End: 151
• Publication Date: 2017-12-10
• Subjects: Diabetes -- Periodicals; 616.462
• DOI: 10.1111/dme.13543
• Languages: English
• ISSNs: 0742-3071

Abstract

Abstract: Aim: To examine the association between mood and anxiety disorders and the development of gestational diabetes mellitus in a retrospective population‐based cohort study. Methods: Clinical data from a provincial perinatal health registry were linked to physician claims, hospitalization records and emergency visits to identify any diagnoses of mood or anxiety disorders in the 2 years prior to pregnancy and a subsequent diagnosis of gestational diabetes during pregnancy. The study population included all singleton pregnancies in the Canadian province of Alberta from 1 April 2000 to 31 March 2010. Generalized estimating equations were used to determine the adjusted odds ratio of gestational diabetes, comparing women with and without a history of mood or anxiety disorders. Results: Among 373 674 pregnancies from 253 911 women, 25.7% had a history of mood or anxiety disorders, and 3.8% developed gestational diabetes. The multivariate‐adjusted odds of developing gestational diabetes were higher among women with a history of mood or anxiety disorders (odds ratio 1.10, 95% CI 1.06–1.14). Conclusions: Women with a history of mood or anxiety disorders had a moderately increased risk of developing gestational diabetes. What's new?: People with mental illness are at an increased risk of developing Type 2 diabetes, but there is limited evidence on the relationship between mental illness and risk of gestational diabetes mellitus (GDM). In a large population‐based cohort, women with a history of mood or anxiety disorders had a greater risk of developing GDM.