DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web‐based tool for identifying protein nearest neighbors using circular dichroism spectroscopy. (25th October 2017)

• Record Type: Journal Article
• Authors: Whitmore, Lee; Mavridis, Lazaros; Wallace, B.A.; Janes, Robert W.
• Is Part Of: Protein science. Volume 27:Number 1(2018)
• Page Start: 10
• Page End: 13
• Publication Date: 2017-10-25
• Subjects: tools for protein characterization -- bioinformatics -- circular dichroism spectroscopy -- secondary structure -- folds; Proteins -- Periodicals; 572.6
• DOI: 10.1002/pro.3207
• Languages: English
• ISSNs: 0961-8368

Abstract

Abstract: Circular dichroism spectroscopy is a well‐used, but simple method in structural biology for providing information on the secondary structure and folds of proteins. DichroMatch (DM@PCDDB) is an online tool that is newly available in the Protein Circular Dichroism Data Bank (PCDDB), which takes advantage of the wealth of spectral and metadata deposited therein, to enable identification of spectral nearest neighbors of a query protein based on four different methods of spectral matching. DM@PCDDB can potentially provide novel information about structural relationships between proteins and can be used in comparison studies of protein homologs and orthologs.