Early Hemodynamic Results in Patients with Small Aortic Annulus after Aortic Valve Replacement. Issue 4 (July 2017)

• Record Type: Journal Article
• Authors: Olivier Dionne, Pierre; Poulin, Frédéric; Bouchard, Denis; Généreux, Philippe; Ibrahim, Reda; Cartier, Raymond; Lamarche, Yoan; Demers, Philippe
• Is Part Of: Innovations. Volume 12:Issue 4(2017)
• Page Start: 254
• Page End: 258
• Publication Date: 2017-07
• Subjects: Aortic valve replacement -- Echocardiography -- Sutureless aortic valve replacement -- Transcatheter aortic valve replacement; Cardiovascular system -- Surgery -- Periodicals; Heart -- Surgery -- Periodicals; Blood-vessels -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; Thoracic Surgical Procedures -- methods -- Periodicals; Vascular Surgical Procedures -- methods -- Periodicals; Thorax -- Chirurgie -- Méthodologie -- Périodiques; Vaisseaux sanguins -- Chirurgie -- Méthodologie -- Périodiques; Blood-vessels -- Surgery; Chest -- Surgery; Periodicals; 617.41
• DOI: 10.1177/155698451701200404
• Languages: English
• ISSNs: 1556-9845

Abstract

Objective: Patients with a small aortic annulus (≤21 mm) have an increased risk of patient-prosthesis mismatch after valve replacement. The aim of this study was to compare the early hemodynamic performance of the balloon-expandable transaortic valve implantation Edwards system (SAPIEN) and the sutureless Perceval prostheses. Methods: Fifty patients underwent transcatheter aortic valve implantation, and 113 patients underwent sutureless aortic valve replacement. Mean ± SD aortic annulus diameter was 19.7 ± 1 mm, with no significant difference between groups. SAPIEN valve size was 23 mm in 40 patients (80%) and 26 mm in 10 patients (20%). Perceval valve size was small in 45 patients (40%), medium in 62 patients (55%), and large in 6 patients (5%). Transthoracic Doppler echocardiographic images were collected at baseline and before discharge. Results: There were no significant difference in predischarge effective orifice area (SAPIEN: 1.5 ± 0.5 cm 2 and Perceval: 1.48 ± 0.34 cm 2, P = 0.58) and indexed effective orifice areas (SAPIEN: 0.93 ± 0.32 cm 2 /m 2 and Perceval: 0.88 ± 0.22 cm 2 /m 2, P = 0.42). Predischarge mean ± SD transaortic gradient was lower with the SAPIEN than with Perceval valves (12 ± 6 and 17 ± 6 mm Hg, respectively, P < 0.001). Rates of moderate and severe prosthesis-patient mismatch were similar (SAPIEN: 44% and 10% and Perceval: 50% and 14%, P = 0.53 and 0.75, respectively). There were no moderate-severe paravalvular leaks. Conclusions: Although indexed effective orifice areas were similar, transcatheter aortic valve implantation with the balloon-expandable SAPIEN system yielded lower predischarge transaortic mean gradients than the surgically implanted Perceval, in patients with a small annulus.