Mining the botulinum research literature. (18th February 2010)

• Record Type: Journal Article
• Authors: Cer, Regina Z.; Mudunuri, Uma; Stephens, Robert M.; Lebeda, Frank J.
• Is Part Of: Botulinum journal. Volume 1:Number 3(2009)
• Page Start: 270
• Page End: 280
• Publication Date: 2010-02-18
• Subjects: batch searches -- batch queries -- information retrieval -- recall -- precision -- F1-measure -- biomedical literature -- literature search -- botulinum resource database -- combinatorial query -- controlled vocabulary -- database searching -- clostridial neurotoxins -- botulinum research; Botulinum toxin -- Periodicals; Clostridium botulinum -- Periodicals; Drug development -- Periodicals; 615.9529364
• Languages: English
• ISSNs: 1754-7318

Abstract

The literature search section (botXminer) in the botulinum resource database (BotDB; http://botdb.abcc.ncifcrf.gov) contains a new query tool – 'Batch Search'. In basic mode, a user can submit a list of words or phrases that are used to conduct a sequential search of the titles, abstracts and MEDLINE contents of clostridial neurotoxin citations. A table of results is returned that contains the numbers of citations found for each query term that are, in turn, linked to information from PubMed and MEDLINE for each citation. In matrix mode, a user can join two lists of user-defined terms in which all of the results from the combinatorial pairs are returned in a matrix. Each matrix element is linked to a citation list. In both modes, searches can be refined by selecting a range of publication years. Examples of 'Batch Search' matrices are statistically analysed for their quality by calculating their recall and precision values.