Dual purpose fibre – SERS pH sensing and bacterial analysis. Issue 24 (5th October 2018)

• Record Type: Journal Article
• Authors: Fleming, Holly; McAughtrie, Sarah; Mills, Bethany; Tanner, Michael G.; Marks, Angus; Campbell, Colin J.
• Is Part Of: Analyst. Volume 143:Issue 24(2018)
• Page Start: 5918
• Page End: 5925
• Publication Date: 2018-10-05
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c8an01322e
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : A way to incorporate SERS nanosensors on the end of an optical fibre that also allows for the extraction of bacterial samples. Abstract : The exploitation of fibre based Raman probes has been challenged by often complicated fabrication procedures and difficulties in reproducibility. Here, we have demonstrated a simple and cost-effective approach for sensing pH through an optical fibre, by employing a wax patterned filter paper-based substrate for surface enhanced Raman spectroscopy (SERS). Through this method, high reproducibility between fibres was achieved. In addition to sensing pH, it was possible to extract fluid samples containing P. aeruginosa for further analysis. This dual purpose fibre is bronchoscope deployable, and is able to gather information about both the host and pathogen, which may lead to an improved treatment plan in future in vivo applications.