Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?. (July 2016)
- Record Type:
- Journal Article
- Title:
- Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?. (July 2016)
- Main Title:
- Glucagon-Like Peptide-1 Receptor Agonists: Beta-Cell Protection or Exhaustion?
- Authors:
- van Raalte, Daniël H
Verchere, C. Bruce - Abstract:
- Abstract : Glucagon-like peptide (GLP)-1 receptor agonists enhance insulin secretion and may improve pancreatic islet cell function. However, GLP-1 receptor (GLP-1R) agonist treatment may have more complex, and sometimes deleterious, effects on beta cells. We discuss the concepts of beta cell protection versus exhaustion for different GLP-1R agonists based on recent data.
- Is Part Of:
- Trends in endocrinology and metabolism. Volume 27:Number 7(2016)
- Journal:
- Trends in endocrinology and metabolism
- Issue:
- Volume 27:Number 7(2016)
- Issue Display:
- Volume 27, Issue 7 (2016)
- Year:
- 2016
- Volume:
- 27
- Issue:
- 7
- Issue Sort Value:
- 2016-0027-0007-0000
- Page Start:
- 442
- Page End:
- 445
- Publication Date:
- 2016-07
- Subjects:
- Glucagon-like peptide (GLP)-1 receptor agonists -- beta-cell protection -- beta-cell exhaustion -- insulin secretion -- chronic treatment
Endocrinology -- Periodicals
Metabolism -- Periodicals
Metabolism
616.4 - Journal URLs:
- http://www.elsevier.com/journals ↗
http://www.sciencedirect.com/science/journal/10432760 ↗ - DOI:
- 10.1016/j.tem.2016.04.009 ↗
- Languages:
- English
- ISSNs:
- 1043-2760
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.590500
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 8842.xml