Transoral laser microsurgery or total laryngectomy for recurrent squamous cell carcinoma of the larynx: Retrospective analysis of 199 cases. Issue 6 (2nd March 2017)

• Record Type: Journal Article
• Authors: Weiss, Bernhard G.; Bertlich, Mattis; Canis, Martin; Ihler, Friedrich
• Is Part Of: Head & neck. Volume 39:Issue 6(2017)
• Page Start: 1166
• Page End: 1176
• Publication Date: 2017-03-02
• Subjects: laryngeal neoplasms -- neoplasm recurrence -- local -- laryngectomy -- transoral laser microsurgery -- retrospective study; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.24737
• Languages: English
• ISSNs: 1043-3074

Abstract

ABSTRACT: Background: Surgical treatment options for local recurrences of laryngeal cancer can be either organ‐preserving surgery or total laryngectomy. The purpose of this study was to present our evaluation of the treatment with transoral laser microsurgery (TLM) in comparison to laryngectomy. Methods: We conducted a retrospective review of 199 consecutive patients with recurrent laryngeal cancer at 1 tertiary referral center. Results: The 5‐year overall survival, disease‐specific survival, and local control rates were 64.8%, 79.6%, and 57.5%, respectively, for 93 patients with early tumors treated by TLM, 28.9%, 41.7%, and 43.7%, respectively, for 52 patients with advanced tumors treated by TLM as well as 39.4%, 44.6%, and 68.8%, respectively, for 54 patients with advanced tumors treated by total laryngectomy. Five‐year larynx‐preservation rate was 77.7% for early as well as 68.4% for advanced tumors treated by TLM. Conclusion: TLM is an option in early and in selected cases of advanced locally recurrent laryngeal cancer. © 2017 Wiley Periodicals, Inc. Head Neck 39: 1166–1176, 2017