Direct Synthesis of Symmetric Diarylethynes from Calcium Carbide and Arylboronic Acids/Esters. Issue 45 (29th November 2017)

• Record Type: Journal Article
• Authors: Fu, Rugang; Li, Zheng
• Is Part Of: European journal of organic chemistry. Issue 45(2017)
• Page Start: 6648
• Page End: 6651
• Publication Date: 2017-11-29
• Subjects: Synthetic methods -- C–C coupling -- Alkynes -- Calcium carbide -- Acetylene source -- Arylboronic acid; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201701234
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : A new methodology for the direct synthesis of symmetric diarylethynes from the reactions of calcium carbide with arylboronic acids/esters is described. Various symmetric diarylethynes were generated from the corresponding arylboronic acids/esters in satisfactory yield by using a palladium catalyst. The advantages of this protocol include the use of a readily available and easy‐to‐handle acetylene source, and a simple work‐up procedure. Abstract : Diarylethynes were efficiently synthesized by commercially available, inexpensive, and easy‐to‐handle calcium carbide with various arylboronic acids/esters. This method avoids the use of flammable and explosive acetylene gas.