Efficient Buchwald–Hartwig–Migita Cross‐Coupling for DNA Thioglycoconjugation. Issue 8 (16th January 2018)
- Record Type:
- Journal Article
- Title:
- Efficient Buchwald–Hartwig–Migita Cross‐Coupling for DNA Thioglycoconjugation. Issue 8 (16th January 2018)
- Main Title:
- Efficient Buchwald–Hartwig–Migita Cross‐Coupling for DNA Thioglycoconjugation
- Authors:
- Probst, Nicolas
Lartia, Rémy
Théry, Océane
Alami, Mouâd
Defrancq, Eric
Messaoudi, Samir - Abstract:
- Abstract: An efficient method for the thioglycoconjugation of iodinated oligonucleotides by Buchwald–Hartwig–Migita cross‐coupling under mild conditions is reported. The method enables divergent synthesis of many different functionalized thioglycosylated ODNs in good yields, without affecting the integrity of the other A, C, and G nucleobases. Abstract : Sweet ODNs : A new strategy for the post functionalization of ODNs is presented. Using Pd‐catalysis, the strategy enabled the synthesis of various thioglycosylated ODNs.
- Is Part Of:
- Chemistry. Volume 24:Issue 8(2018)
- Journal:
- Chemistry
- Issue:
- Volume 24:Issue 8(2018)
- Issue Display:
- Volume 24, Issue 8 (2018)
- Year:
- 2018
- Volume:
- 24
- Issue:
- 8
- Issue Sort Value:
- 2018-0024-0008-0000
- Page Start:
- 1795
- Page End:
- 1800
- Publication Date:
- 2018-01-16
- Subjects:
- DNA-glycoconjugates -- oligonucleotides -- Pd catalysis -- thioglycoconjugation -- thiosaccharide
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3765 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/chem.201705371 ↗
- Languages:
- English
- ISSNs:
- 0947-6539
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3168.860500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 8821.xml