A Lacrimal Gland Choristoma of the Lacrimal Sac. Issue 1 (January 2018)

• Record Type: Journal Article
• Authors: Wang, Yvonne; Jakobiec, Frederick A.; Zakka, Fouad R.; Lee, Nahyoung Grace
• Is Part Of: Ophthalmic plastic and reconstructive surgery. Volume 34:Issue 1(2018)
• Publication Date: 2018-01
• Subjects: Eye -- Surgery -- Periodicals; Ophthalmic plastic surgery -- Periodicals; Reconstructive Surgical Procedures -- Periodicals; Ophthalmologic Surgical Procedures -- Periodicals; Ophthalmology -- Periodicals; Surgery -- Periodicals; 617.70592
• DOI: 10.1097/IOP.0000000000000953
• Languages: English
• ISSNs: 0740-9303

Abstract

Abstract : Choristomatous lacrimal gland tissue has been detected in many different sites of the ocular adnexa, but has never before been convincingly described in the submucosa of the lacrimal sac. A 77-year-old woman with epiphora had a biopsy of the sac wall preformed during a dacryocystorhinostomy that contained such a lacrimal choristoma. Zymogen granules were found in the cytoplasm of the secretory cells with the periodic acid-Schiff reaction. No mucus-producing cells, as found in normal sac submucosal glands, were detected using the Alcian blue, mucicarmine, and Gomori methenamine silver histochemical stains. Gross cystic fluid protein-15 positivity was demonstrated immunohistochemically. The clinical implications of this choristoma are explored. Abstract : The wall of the lacrimal sac was biopsied during a dacryocystorhinostomy for epiphora and was discovered to contain the first well-characterized example of a lacrimal gland choristoma.