A rapid construction of the ABC tricyclic skeleton of malabanone A. Issue 44 (1st November 2018)

• Record Type: Journal Article
• Authors: Li, Tao; Wu, Guangmiao; Feng, Shangbiao; Wang, Zemin; Xie, Xingang; She, Xuegong
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 44(2018)
• Page Start: 8491
• Page End: 8494
• Publication Date: 2018-11-01
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob02495b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The ABC tricyclic skeleton of malabanone A was accomplished in a concise route starting from R -carvone. Abstract : The construction of the ABC tricyclic skeleton of malabanone A with the required 4 stereocenters was accomplished in a concise route starting from R -carvone. The synthesis featured an intramolecular [3 + 2] cycloaddition reaction to assemble its A ring and an intramolecular Diels–Alder reaction to construct its C ring.