Palladium-catalyzed olefination of aryl/alkyl halides with trimethylsilyldiazomethane via carbene migratory insertion. Issue 92 (2nd November 2018)

• Record Type: Journal Article
• Authors: Mu, Qiu-Chao; Wang, Xing-Ben; Ye, Fei; Sun, Yu-Li; Bai, Xing-Feng; Chen, Jing; Xia, Chun-Gu; Xu, Li-Wen
• Is Part Of: Chemical communications. Volume 54:Issue 92(2018)
• Page Start: 12994
• Page End: 12997
• Publication Date: 2018-11-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc07664b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : One-pot formation of ( E )-vinyl silanes and ( E )-silyl-substituted α, β-unsaturated amides could be completed easily via palladium carbene migratory insertion in good yields and high chemoselectivity. Abstract : The direct olefination of aryl/alkyl halides with trimethylsilyldiazomethane (TMSD) as a C1- or C2-unit was achieved successfully via a metal carbene migratory insertion process, which offered a new access to afford ( E )-vinyl silanes and ( E )-silyl-substituted α, β-unsaturated amides in good yields and high chemoselectivity.