A Case of Ivermectin-Induced Warfarin Toxicity: First Published Report. (December 2018)

• Record Type: Journal Article
• Authors: Gilbert, Brian Wesley; Slechta, Joe
• Is Part Of: Hospital pharmacy. Volume 53:Number 6(2018)
• Page Start: 393
• Page End: 394
• Publication Date: 2018-12
• Subjects: adverse drug reactions -- anticoagulants -- anti-infectives -- drug interactions -- Warfarin; Hospital pharmacies -- Periodicals; Pharmacy Service, Hospital; Hospital pharmacies; Periodicals; Periodicals; 615.1
• DOI: 10.1177/0018578718758972
• Languages: English
• ISSNs: 0018-5787

Abstract

Here, we present the case of a patient who developed a large hematoma under his tongue while taking concomitant warfarin and ivermectin. Ivermectin has been shown to interfere with vitamin K–dependent clotting factors II, V, VII, and X. However, all the data to date have been from in vivo data with little to no reports on its effects on humans. To our knowledge, this is the first case report to present such a case.