Prevalence of carriage of extended-spectrum β-lactamase-producing enterobacteria and associated factors in a French hospital. (December 2018)

• Record Type: Journal Article
• Authors: Jolivet, S.; Vaillant, L.; Poncin, T.; Lolom, I.; Gaudonnet, Y.; Rondinaud, E.; Bendjelloul, G.; Lomont, A.; Lucet, J.-C.; Armand-Lefèvre, L.
• Is Part Of: Clinical microbiology and infection. Volume 24:Number 12(2018)
• Page Start: 1311
• Page End: 1314
• Publication Date: 2018-12
• Subjects: Associated factors -- Carriage -- Enterobacteriaceae -- Extended-spectrum β-lactamase (ESBL)-producing enterobacteria -- Prevalence; Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1016/j.cmi.2018.03.008
• Languages: English
• ISSNs: 1198-743X

Abstract

Abstract: Objectives: Our aim was to evaluate the prevalence and associated factors for carriage of extended-spectrum β-lactamase-producing enterobacteria (ESBL-PE) in a healthcare facility. Methods: In 2016 a serial cross-sectional survey of ESBL-PE carriage in a French university hospital was conducted. All patients present on the day of the survey were screened for ESBL-PE carriage. Demographic characteristics and risk factors for ESBL-PE carriage were collected. Results: In all, 146/844 patients (17%) were digestive carriers of ESBL-PE; of these, 96 (66%) had not previously been identified. Among patients carrying ESBL-PE, Escherichia coli (62%) and CTX-M type (94%) predominated. Greater age, recent travel abroad, receipt of antibiotic, and prolonged hospitalization were associated with ESBL-PE carriage. Conclusion: Given the high prevalence of ESBL-PE and the high proportion of unknown carriers, our results strongly suggest reinforcing standard precautions rather than contact precautions for controlling the spread of ESBL-PE.