The etiology of potential small-bowel bleeding depending on patient's age and gender. Issue 8 (October 2018)

• Record Type: Journal Article
• Authors: Song, Joo Hye; Hong, Sung Noh; Kyung Chang, Dong; Ran Jeon, Seong; Kim, Jin-Oh; Kim, Jinsu; Lee, Bo-In; Choi, Myung-Gyu; Kim, Kyeong Ok; Yang, Dong-Hoon; Song, Hyun Joo; Hyuk Do, Jae; Jeong Lim, Yun; Shim, Ki-Nam; Park, Soo Jung; Kim, Ji Hyun; Moon, Jeong Seop; Joo Jang, Hyun; Jai Chun, Hoon
• Is Part Of: United European Gastroenterology journal. Volume 6:Issue 8(2018)
• Page Start: 1169
• Page End: 1178
• Publication Date: 2018-10
• Subjects: Potential small-bowel bleeding -- obscure gastrointestinal bleeding -- video capsule endoscopy -- age -- gender; Gastroenterology -- Periodicals; Periodicals; 616.33005
• DOI: 10.1177/2050640618797841
• Languages: English
• ISSNs: 2050-6406

Abstract

Background: Whether the etiology of potential small-bowel bleeding depends on the age and gender of the patient is not yet fully understood. Methods: A total of 1953 patients who underwent video capsule endoscopy (VCE) to evaluate potential small-bowel bleeding and were registered in the Capsule Endoscopy Nationwide Database Registry from 2003 to 2014 were eligible for this study. VCE findings and the etiology of small-bowel bleeding were analyzed by age and gender. Results: The diagnostic yield of VCE was 48.4% (95% CI: 46.2%–50.6%) and the diagnosis rate of etiology of potential small-bowel bleeding was 61.4% (95% CI: 59.2%–63.6%). The etiology of potential small-bowel bleeding depends on the age and gender of the patient. Crohn's disease and small-bowel diverticular diseases were more prevalent etiology of potential small-bowel bleeding in the young adults group (< 40 years) whereas angiodysplasia was revealed to be a most common etiology in elderly group (≥ 60 years), reaching statistical significance ( p <0.00152) by Bonferroni correction. Conclusions: The etiology of potential small-bowel bleeding depends on the age of the patient. Thus, an individualized lesion-specific diagnostic approach based on age might be needed for patients with potential small-bowel bleeding.