Role of Functional Imaging in Treatment Plan Optimization of Stereotactic Body Radiation Therapy for Liver Cancer. Issue 5 (September 2016)

• Record Type: Journal Article
• Authors: De Bari, Berardino; Jumeau, Raphael; Deantonio, Letizia; Adib, Salim; Godin, Sarah; Zeverino, Michele; Moeckli, Raphael; Bourhis, Jean; Prior, John O.; Ozsahin, Mahmut
• Is Part Of: Tumori. Volume 102:Issue 5(2016)
• Page Start: e21
• Page End: e24
• Publication Date: 2016-09
• Subjects: 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) -- Liver cancer -- Hepatocellular carcinoma -- Stereotactic body radiation therapy (SBRT) -- Toxicity; Cancer -- Periodicals; 616.994
• DOI: 10.5301/tj.5000523
• Languages: English
• ISSNs: 0300-8916

Abstract

We report the first known instance of the clinical use of 99m Tc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.