Translation and validation of the 15‐item Myasthenia Gravis Quality of life scale in Dutch. Issue 2 (9th May 2017)

• Record Type: Journal Article
• Authors: Strijbos, Ellen; Gärtner, Fania R.; Verschuuren, Jan J.
• Is Part Of: Muscle & nerve. Volume 57:Issue 2(2018)
• Page Start: 206
• Page End: 211
• Publication Date: 2017-05-09
• Subjects: myasthenia gravis -- MG‐QOL15 -- outcome measure -- translation -- validation; Neuromuscular diseases -- Periodicals; Muscles -- Periodicals; Nerves -- Periodicals; 616.74
• DOI: 10.1002/mus.25641
• Languages: English
• ISSNs: 0148-639X

Abstract

ABSTRACT: Introduction: The 15‐item Myasthenia Gravis Quality of Life (MG‐QOL15) scale has been developed to assess the health‐related quality of life of patients with myasthenia gravis (MG). The aim of this study was to translate the original English version into Dutch and to test the test–retest reliability and construct validity. Methods: Fifty patients with MG were included. Test–retest reliability and internal consistency were assessed using the intraclass correlation coefficient (ICC) and the Cronbach α. Construct validity was assessed by testing 5 predefined hypotheses. Results: A good test–retest reliability was confirmed with an ICC of 0.866. The Cronbach α was 0.93. The predefined hypotheses were confirmed in 80% of cases, which points to good construct validity. Discussion: The Dutch MG‐QOL15 has good test–retest reliability and good construct validity. It can be used for research in a Dutch‐speaking population. It is also suitable for monitoring individual patients in clinical practice. Muscle Nerve 57 : 206–211, 2018