68Ga–Prostate-Specific Membrane Antigen Uptake in Gastrointestinal Stromal Tumor. (January 2018)

• Record Type: Journal Article
• Authors: Laurens, Tom; Witjes, Fred; Janssen, Marcel; Flucke, Uta; Gottardt, Martin
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 1(2018)
• Publication Date: 2018-01
• Subjects: 68Ga-PSMA -- gastrointestinal stromal tumor -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001902
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 62-year-old man with recently diagnosed prostatic adenocarcinoma was referred for a whole-body 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT scan for staging. Although the scan did not reveal metastatic disease, it did reveal a PSMA-avid lesion in the upper abdomen located between the liver and the stomach. Histopathologic examination demonstrated a gastrointestinal stromal tumor. The lesion demonstrated increased uptake in the margins of the tumor with a central photopenic area, which we consider to be the typical pattern on PSMA images of a gastrointestinal stromal tumor, based on theoretical PSMA distribution in such a tumor and other reported cases.