Testicular Estrogen-Secreting Leydig Cell Tumor in 18F-FDG PET/CT: An Incidental Detection in a Patient Treated by Chemotherapy for Hodgkin Lymphoma. (January 2018)

• Record Type: Journal Article
• Authors: Van Der Gucht, Axel; Maged, Zaher; Burruni, Rodolfo; Barras, Jean-Luc; Schaefer, Niklaus
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 1(2018)
• Publication Date: 2018-01
• Subjects: 18F-FDG -- Leydig cell tumor -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001905
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We present images of a 50-year-old man who referred for treatment of a classic Hodgkin lymphoma. While 18 F-FDG PET/CT demonstrated a complete metabolic remission after chemotherapy, an increased 18 F-FDG uptake of a right testicular lesion in 18 F-FDG PET/CT and an unexplained bilateral gynecomastia were observed. A benign Leydig cell tumor was histopathologically proved after a right radical orchiectomy. The serum estradiol level was abnormally elevated reflecting the estrogen-secreting profile. This report highlights that a focal 18 F-FDG uptake in the testicular region with unexplained gynecomastia should suggest the diagnosis of an estrogen-secreting Leydig cell tumor on 18 F-FDG PET/CT.