111In-DTPA-Octreotide SPECT (OctreoScan) Uptake in Metastatic Renal Cell Carcinoma to the Pancreas. (January 2018)

• Record Type: Journal Article
• Authors: Chan, Kenneth; Luong, Tu Vinh; Navalkissoor, Shaunak
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 1(2018)
• Publication Date: 2018-01
• Subjects: 111In-DTPA-octreotide SPECT -- pancreatic neuroendocrine neoplasm -- renal cell carcinoma -- somatostatin receptor; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001898
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We report a case of late presentation of metastatic renal cell carcinoma (RCC) demonstrating intense 111 In-DTPA-octreotide uptake in pancreas without recurrence at the primary site. Immunohistochemistry study revealed somatostatin receptor subtype 2 of metastatic RCC preferentially expressed on tumor endothelial cells. The typical hypervascular features of RCC with intense homogeneous contrast enhancement in the arterial phase on CT should raise the possibility of metastatic RCC. This case illustrates that RCC can demonstrate high octreotide uptake in abdominal metastases.