Direct Synthesis of Amides by Dehydrogenative Coupling of Amines with either Alcohols or Esters: Manganese Pincer Complex as Catalyst. Issue 47 (20th October 2017)

• Record Type: Journal Article
• Authors: Kumar, Amit; Espinosa‐Jalapa, Noel Angel; Leitus, Gregory; Diskin‐Posner, Yael; Avram, Liat; Milstein, David
• Is Part Of: Angewandte Chemie international edition. Volume 56:Issue 47(2017)
• Page Start: 14992
• Page End: 14996
• Publication Date: 2017-10-20
• Subjects: amides -- amines -- ligand design -- manganese -- structure elucidation; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201709180
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: The first example of base‐metal‐catalysed synthesis of amides from the coupling of primary amines with either alcohols or esters is reported. The reactions are catalysed by a new manganese pincer complex and generate hydrogen gas as the sole byproduct, thus making the overall process atom‐economical and sustainable. Abstract : Just a pinc(h) : The first example of base‐metal‐catalysed synthesis of amides from the coupling of primary amines with either alcohols or esters is reported. The reactions are catalysed by a new manganese pincer complex and generate hydrogen gas as the sole byproduct, thus making the overall process atom‐economical and sustainable.