Validity and reliability of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) in Japanese patients with bipolar disorder. (August 2017)

• Record Type: Journal Article
• Authors: Toyoshima, Kuniyoshi; Fujii, Yutaka; Mitsui, Nobuyuki; Kako, Yuki; Asakura, Satoshi; Martinez-Aran, Anabel; Vieta, Eduard; Kusumi, Ichiro
• Is Part Of: Psychiatry research. Volume 254(2017)
• Page Start: 85
• Page End: 89
• Publication Date: 2017-08
• Subjects: COBRA Cognitive Complaints in Bipolar Disorder Rating Assessment -- FCQ Frankfurt Complaint Questionnaire -- CDS Cognitive Difficulties Scale -- CFQ Cognitive Failures Questionnaire -- PAOF Patient's Assessment of Own Functioning -- DSM-5 Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition -- HAM-D Hamilton Rating Scale for Depression -- YMRS Young Mania Rating Scale -- JART-25 Japanese Adult Reading Test-25 -- WCST Wisconsin Card Sorting Test -- WFT Word Fluency Test -- CPT Continuous Performance Test -- TMT Trail Making Test -- AVLT Auditory Verbal Learning Test; Subjective cognitive impairment -- Japan -- Neuropsychological tests -- Cognition -- COBRA -- Bipolar disorder; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2017.04.043
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: In Japan, there are currently no reliable rating scales for the evaluation of subjective cognitive impairment in patients with bipolar disorder. We studied the relationship between the Japanese version of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) and objective cognitive assessments in patients with bipolar disorder. We further assessed the reliability and validity of the COBRA. Forty-one patients, aged 16–64, in a remission period of bipolar disorder were recruited from Hokkaido University Hospital in Sapporo, Japan. The COBRA (Japanese version) and Frankfurt Complaint Questionnaire (FCQ), the gold standard in subjective cognitive assessment, were administered. A battery of neuropsychological tests was employed to measure objective cognitive impairment. Correlations among the COBRA, FCQ, and neuropsychological tests were determined using Spearman's correlation coefficient. The Japanese version of the COBRA had high internal consistency, good retest reliability, and concurrent validity—as indicated by a strong correlation with the FCQ. A significant correlation was also observed between the COBRA and objective cognitive measurements of processing speed. These findings are the first to demonstrate that the Japanese version of the COBRA may be clinically useful as a subjective cognitive impairment rating scale in Japanese patients with bipolar disorder. Highlights: The psychometric properties of the COBRA in Japanese bipolar patients are unknown. Test-retest reliability of the COBRA was confirmed in this patient population. The COBRA is valid and reliable for assessing subjective cognitive impairment.