How Does an Anti-CTLA-4 Antibody Promote Cancer Immunity?. Issue 12 (December 2018)
- Record Type:
- Journal Article
- Title:
- How Does an Anti-CTLA-4 Antibody Promote Cancer Immunity?. Issue 12 (December 2018)
- Main Title:
- How Does an Anti-CTLA-4 Antibody Promote Cancer Immunity?
- Authors:
- Liu, Yang
Zheng, Pan - Abstract:
- Abstract : Anti-CTLA-4 antibodies can induce lasting protection for some melanoma patients. However, their therapeutic potential is limited by significant immunotherapy-related adverse effects (irAE). Here, we argue that the therapeutic effect may be based on an agonist activity that is fundamentally distinct, and can be therapeutically differentiated, from the antagonist activity responsible for irAE.
- Is Part Of:
- Trends in immunology. Volume 39:Issue 12(2018)
- Journal:
- Trends in immunology
- Issue:
- Volume 39:Issue 12(2018)
- Issue Display:
- Volume 39, Issue 12 (2018)
- Year:
- 2018
- Volume:
- 39
- Issue:
- 12
- Issue Sort Value:
- 2018-0039-0012-0000
- Page Start:
- 953
- Page End:
- 956
- Publication Date:
- 2018-12
- Subjects:
- Immunology -- Periodicals
571.96 - Journal URLs:
- http://www.sciencedirect.com/science/journal/14714906 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.it.2018.10.009 ↗
- Languages:
- English
- ISSNs:
- 1471-4906
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.630500
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 8679.xml