Electrocardiographic simulation on personalised heart-torso structures using coupled meshfree-BEM platform. (3rd August 2009)

• Record Type: Journal Article
• Authors: Wang, Linwei; Zhang, Heye; Wong, Ken C.L.; Liu, Huafeng; , Pengcheng Shi
• Is Part Of: International journal of functional informatics and personalised medicine. Volume 2:Number 2(2009)
• Page Start: 175
• Page End: 200
• Publication Date: 2009-08-03
• Subjects: electrocardiography -- TMP imaging -- transmembrane potentials -- BSP -- body surface potentials -- tomographic images -- meshfree methods -- boundary element method -- BEM -- simulation -- personalised medicine -- heart-torso structures -- electrocardiographic modelling -- post myocardial infarction; Biomedical engineering -- Periodicals; Bioinformatics -- Periodicals; 610.28
• Languages: English
• ISSNs: 1756-2104

Abstract

The foremost premise for the success of noninvasive volumetric myocardial Transmembrane (TMP) imaging from Body Surface Potential (BSP) recordings is a realistic yet efficient TMP-to-BSP mapping model that balances model accuracy with reconstruction feasibility. This papers presents a novel coupled meshfree-BEM platform to this forward electrocardiographic modelling. Its numerical accuracy and convergence is quantitatively assessed against analytical solutions on a synthetic geometry. Electrocardiographic simulations of various cardiac conditions on personalised heart-torso structures are consistent with existent experimental studies. In further real data validations on three post myocardial infarction patients, simulated BSP exhibit high accuracy compared to measured BSP.