Biphasic malignant melanoma adenocarcinoma in the digit of a dog. (March 2018)

• Record Type: Journal Article
• Authors: Needle, David B.; Iglikova, Olga; Miller, Andrew D.
• Is Part Of: Journal of veterinary diagnostic investigation. Volume 30:Number 2(2018:Mar.)
• Page Start: 315
• Page End: 318
• Publication Date: 2018-03
• Subjects: Adenocarcinoma -- biphasic neoplasms -- dogs -- melanoma; Veterinary medicine -- Diagnosis -- Periodicals; 636.0896075
• DOI: 10.1177/1040638717752424
• Languages: English
• ISSNs: 1040-6387

Abstract

A 7-y-old Black Russian Terrier dog was evaluated for chronic lameness of the right forelimb and concurrent weight loss. Clinical examination revealed a pigmented mass arising from digit 4 of the right forelimb; the digit was amputated and submitted for histologic evaluation. Histologically, the neoplasm was composed of ill-defined streams, sheets, and clusters of melanocytes admixed with a distinct population of malignant epithelial cells forming glands and nests. The diagnosis was a biphasic malignant melanoma adenocarcinoma, a rarely reported neoplasm in human medicine that has not been described in veterinary medicine, to our knowledge.