Causes and treatments of achalasia, and primary disorders of the esophageal body. (11th October 2013)

• Record Type: Journal Article
• Authors: Felix, Valter Nilton; DeVault, Kenneth; Penagini, Roberto; Elvevi, Alessandra; Swanstrom, Lee; Wassenaar, Eelco; Crespin, Oscar M.; Pellegrini, Carlos A.; Wong, Roy
• Is Part Of: Annals of the New York Academy of Sciences. Volume 1300(2013)
• Page Start: 236
• Page End: 249
• Publication Date: 2013-10-11
• Subjects: achalasia -- GERD -- swallowing -- relaxation -- esophogastric junction -- nutcracker esophagus; Medical sciences -- Periodicals; Medicine -- Periodicals; Science -- Periodicals; 610
• DOI: 10.1111/nyas.12254
• Languages: English
• ISSNs: 0077-8923

Abstract

Abstract : The following on achalasia and disorders of the esophageal body includes commentaries on controversies regarding whether patients with complete lower esophageal sphincter (LES) relaxation can be considered to exhibit early achalasia; the roles of different mucle components of the LES in achalasia; sensory neural pathways impaired in achalasia; indications for peroral endoscopic myotomy and advantages of the technique over laparoscopic and thorascopic myotomy; factors contributing to the success of surgical therapy for achalasia; modifications to the classification of esophageal body primary motility disorders in the advent of high‐resolution manometry (HRM); analysis of the LES in differentiating between achalasia and diffuse esophageal spasm (DES); and appropriate treatment for DES, nutcracker esophagus (NE), and hypertensive LES (HTLES).