Defining esophageal landmarks, gastroesophageal reflux disease, and Barrett's esophagus. (11th October 2013)

• Record Type: Journal Article
• Authors: DeVault, Kenneth; McMahon, Barry P.; Celebi, Altay; Costamagna, Guido; Marchese, Michele; Clarke, John O.; Hejazi, Reza A.; McCallum, Richard W.; Savarino, Vincenzo; Zentilin, Patrizia; Savarino, Edoardo; Thomson, Mike; Souza, Rhonda F.; Donohoe, Claire L.; O'Farrell, Naoimh J.; Reynolds, John V.
• Is Part Of: Annals of the New York Academy of Sciences. Volume 1300(2013)
• Page Start: 278
• Page End: 295
• Publication Date: 2013-10-11
• Subjects: manometry -- GERD -- dysphagia -- NERD -- endoscopy; Medical sciences -- Periodicals; Medicine -- Periodicals; Science -- Periodicals; 610
• DOI: 10.1111/nyas.12253
• Languages: English
• ISSNs: 0077-8923

Abstract

Abstract : The following paper on gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) includes commentaries on defining esophageal landmarks; new techniques for evaluating upper esophageal sphincter (UES) tone; differential diagnosis of GERD, BE, and hiatal hernia (HH); the use of high‐resolution manometry for evaluation of reflux; the role of fundic relaxation in reflux; the use of 24‐h esophageal pH–impedance testing in differentiating acid from nonacid reflux and its potential inclusion in future Rome criteria; classification of endoscopic findings in GERD; the search for the cell origin that generates BE; and the relationship between BE, Barrett's carcinoma, and obesity.