Biologic Joint Repair Strategies: The Mizzou BioJoint Story. (October 2017)

• Record Type: Journal Article
• Authors: Kuroki, Keiichi; Stoker, Aaron M.; Stannard, James P.; Bozynski, Chantelle C.; Cook, Cristi R.; Pfeiffer, Ferris M.; Cook, James L.
• Other Names: Gropp Katheryn guest-editor.; Boyle Michael guest-editor.
• Is Part Of: Toxicologic pathology. Volume 45:Number 7(2017)
• Page Start: 931
• Page End: 938
• Publication Date: 2017-10
• Subjects: osteoarthritis -- cartilage -- osteochondral allograft; Pathology -- Periodicals; Toxicology -- Periodicals; Pathology; Toxicology; 615.9
• DOI: 10.1177/0192623317735786
• Languages: English
• ISSNs: 0192-6233

Abstract

Because articular cartilage has very limited healing potential, most symptomatic cartilage injuries eventually result in end-stage osteoarthritis and are treated with artificial joint replacement. Our interdisciplinary, comparative orthopedic research performed by a team of DVMs, MDs, engineers, and basic scientists has yielded marked progress toward effective biologic joint restoration strategies by bringing bench-side ideas to fruition in bedside applications in both canine and human patients. This mini-review summarizes the progress of biologic joint restoration strategies at our center.