Effect of human albumin on corrosion and biological behavior of CoCrMo. Issue 8 (27th February 2017)

• Record Type: Journal Article
• Authors: Ionita, D.; Golgovici, F.; Demetrescu, I.; Sajin, M.; Pandelea‐Dobrovicescu, G.‐R.
• Is Part Of: Materials and corrosion. Volume 68:Issue 8(2017)
• Page Start: 876
• Page End: 882
• Publication Date: 2017-02-27
• Subjects: CoCrMo alloy -- EIS -- hemocompatibility -- kinetic parameter of corrosion; Materials -- Periodicals; Metals -- Periodicals; Corrosion and anti-corrosives -- Periodicals; 620.1122305
• DOI: 10.1002/maco.201609406
• Languages: English
• ISSNs: 0947-5117

Abstract

Abstract : The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy The electrochemical behavior of the alloy was tested in SBF with and without HSA. The used electrochemical methods have been open circuit potential measurement, potentiodynamic polarization, and electrochemical impedance spectroscopy. Albumin adsorption has been evaluated spectrophotometrically using both FT–IR and UV–VIS investigation methods. The human albumin acts as an inhibitor of corrosion reducing corrosion current until five time. The mechanism of inhibition is due to a protective barrier based on a complex metal‐protein formation and evidenced by impedance spectroscopy procedure. Biological tests confirmed non hemocompatibility of CoCrMo alloy and a non trombogenic behavior. No blood cell shape modification was observed as well. Abstract : The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy. The human albumin act as an inhibitor of corrosion reducing corrosion current until five time. Biological tests confirmed non hemocompatibility of CoCrMo alloy and a non trombogenic behaviour. No blood cell shape modification was observed as well.